Automated image processing pipeline for adaptive optics scanning light ophthalmoscopy
نویسندگان
چکیده
منابع مشابه
Adaptive optics scanning laser ophthalmoscopy.
We present the first scanning laser ophthalmoscope that uses adaptive optics to measure and correct the high order aberrations of the human eye. Adaptive optics increases both lateral and axial resolution, permitting axial sectioning of retinal tissue in vivo. The instrument is used to visualize photoreceptors, nerve fibers and flow of white blood cells in retinal capillaries.
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PURPOSE To develop an automated reference frame selection (ARFS) algorithm to replace the subjective approach of manually selecting reference frames for processing adaptive optics scanning light ophthalmoscope (AOSLO) videos of cone photoreceptors. METHODS Relative distortion was measured within individual frames before conducting image-based motion tracking and sorting of frames into distinc...
متن کاملHuman retinal microvascular imaging using adaptive optics scanning light ophthalmoscopy
BACKGROUND Retinal microvascular imaging is an especially promising application of high resolution imaging since there are increasing options for therapeutic intervention and need for better structural and functional biomarkers to characterize ocular and systemic vascular diseases. MAIN BODY Adaptive optics scanning light ophthalmoscopy (AOSLO) is an emerging technology for improving in vivo ...
متن کاملAdaptive optics scanning ophthalmoscopy with annular pupils
Annular apodization of the illumination and/or imaging pupils of an adaptive optics scanning light ophthalmoscope (AOSLO) for improving transverse resolution was evaluated using three different normalized inner radii (0.26, 0.39 and 0.52). In vivo imaging of the human photoreceptor mosaic at 0.5 and 10° from fixation indicates that the use of an annular illumination pupil and a circular imaging...
متن کاملMEMS-based adaptive optics scanning laser ophthalmoscopy.
We have developed a compact, robust adaptive optics (AO) scanning laser ophthalmoscope using a microelectromechanical (MEMS) deformable mirror (DM). Facilitated with a Shack-Hartmann wavefront sensor, the MEMS-DM-based AO operates a closed-loop modal wave aberration correction for the human eye and reduces wave aberrations in most eyes to below 0.1 microm rms. Lateral resolution is enhanced, an...
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ژورنال
عنوان ژورنال: Biomedical Optics Express
سال: 2021
ISSN: 2156-7085,2156-7085
DOI: 10.1364/boe.418079